Spine
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Comparative Study
The distribution of tissue damage in the spinal cord is influenced by the contusion velocity.
A rat model of thoracic spinal cord contusion was used to examine the effect of velocity on the primary injury. ⋯ We conclude that contusion velocity has an effect on the magnitude of injury within the white matter during spinal cord injury and the amount of neuronal damage in the gray matter. The results of this study demonstrate the importance of including high impact velocity as a variable in models of spinal cord injury.
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Prospective cohort study. ⋯ The results suggest that causal beliefs may play a major role in the perceived disability and course of neck complaints after motor vehicle accidents, whereas pain catastrophizing is predominantly related to concurrent disability.The current findings are consistent with the view that an early conviction that neck complaints are caused by the medico-cultural entity whiplash has a detrimental effect on the course of symptoms.
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A cross-sectional study. ⋯ Our study highlights the fact that limited physical activity results in high bone turnover rate in patients with LSS.
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Biomechanical assessment using calf lumbar motion segments. ⋯ Facetectomy causes a nominal increase in ROM and NZ in FE and LB, which are not affected by the addition of a crosslink. Although the effect of facetectomy is greater in AR-and crosslink has a measurable restoring effect-all differences are within a few tenths of a degree under this loading paradigm. Thus, the clinical utility of adding a crosslink may not be justified based on these small biomechanical changes. COM can serve as a complement to ROM and NZ, or even as a surrogate when its 2 components are reported together, as it shows strong agreement with ROM, effectively distinguishes between lax and elastic region behaviors, and provides a measure of flexibility independent of the load range.
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Immunohistological and behavioral analysis of the effect of a tumor necrosis factor alpha (TNF-alpha) inhibitor in an injured-nerve model. ⋯ Our results indicate that direct application of a TNF-alpha inhibitor had a small effect on acute pain behavior and may not be effective for suppression of inflammatory peptides in the current disc-herniation model.