Spine
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Randomized Controlled Trial Multicenter Study
Education of patients after whiplash injury: is oral advice any better than a pamphlet?
Randomized parallel-group trial with 1-year follow-up. ⋯ Prognosis did not differ between patients who received personal education and those who got a pamphlet. However, a systematic tendency toward better outcome with personal communicated information was observed and the question how patients should be educated to reduce the risk of chronicity after whiplash is worth further investigation, since no treatment have been proven to prevent long-lasting symptoms, and all forms of advice or educational therapy are so cheap that even a modest effect justifies its use.
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Randomized Controlled Trial
Therapeutic effect of intrathecal morphine after posterior lumbar interbody fusion surgery: a prospective, double-blind, randomized study.
Prospective, double-blind, randomized, placebo-controlled study. ⋯ We demonstrated the efficacy of 0.4 mg intrathecal morphine after PLIF-surgery as indicated by a significantly lower cumulative piritramide requirement without any serious increase of opioid associated side effects. Therefore, morphine in a dose of 0.4 mg administered intrathecally seems to be a viable alternative therapeutic option to provide postoperative analgesia with PLIF-surgery.
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Randomized Controlled Trial Multicenter Study Comparative Study
The effectiveness of manual physical therapy and exercise for mechanical neck pain: a randomized clinical trial.
Randomized clinical trial. ⋯ An impairment-based MTE program resulted in clinically and statistically significant short- and long-term improvements in pain, disability, and patient-perceived recovery in patients with mechanical neck pain when compared to a program comprising advice, a mobility exercise, and subtherapeutic ultrasound.
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Randomized Controlled Trial Multicenter Study Comparative Study
The MRC spine stabilization trial: surgical methods, outcomes, costs, and complications of surgical stabilization.
A review of the surgical costs and results in a group of patients randomly allocated to surgery as part of a large prospective randomized trial of patients with chronic back pain. ⋯ These observational changes in the ODI after surgery are similar to those reported from other studies of spinal fusion. More complex surgery is more expensive with more complications than postero-lateral fusion.
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Randomized Controlled Trial Comparative Study
Urgent surgical decompression compared to methylprednisolone for the treatment of acute spinal cord injury: a randomized prospective study in beagle dogs.
Experimental dog model of acute spinal cord injury. ⋯ In the setting of acute and persistent spinal cord compression in beagle dogs, surgical decompression 6 hours after injury, with or without methylprednisolone, is more effective for improving neurologic recovery than methylprednisolone alone.