Spine
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Randomized Controlled Trial Multicenter Study
Efficacy and safety of duloxetine in patients with chronic low back pain.
This was a randomized, double-blind, placebo-controlled clinical trial. ⋯ Duloxetine significantly reduced pain and improved functioning in patients with CLBP. The safety and tolerability were similar to those reported in earlier studies.
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Cochrane systematic review. ⋯ There is very low quality evidence in favor of using braces, making generalization very difficult. Further research could change the actual results and our confidence in them; in the meantime, patients' choices should be informed by multidisciplinary discussion. Future research should focus on short- and long-term patient-centered outcomes, in addition to measures such as Cobb angles. RCTs and prospective cohort studies should follow both the Scoliosis Research Society and Society on Scoliosis Orthopedic and Rehabilitation Treatment criteria for bracing studies.
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Review Case Reports
A modified decompression surgery for thoracic myelopathy caused by ossification of posterior longitudinal ligament: a case report and literature review.
Case report and review. ⋯ The present case suggests that posterior decompression, anterior extirpation of OPLL, and interbody fusion with spinal instrumentation only via a modified posterior-lateral approach is a novel, safe, and effective procedure for surgical treatment of thoracic OPLL.
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Twelve-month cohort study. ⋯ In association with fear of work, 2 factors from the adapted stress process model are significantly useful for predicting LBP related long-term disability outcomes and could be targeted by preventive interventions.
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A cross sectional study of thoracic pedicle morphometry in the immature spine of Malaysian population using reformatted computed tomographic (CT) images. ⋯ The isthmus endosteal width in >50% of the pedicles studied were less than 3.0 mm. We conclude that transpedicular fixation in the thoracic spine using pedicle screw of >3.0 mm diameter is not feasible in children and adolescents of <18 years old in our population.