Spine
· Jun 2010
Randomized Controlled Trial
Multicenter Study
Randomized trial and concurrent observational cohort study. ⋯ Patients with symptomatic spinal stenosis treated surgically compared to those treated nonoperatively maintain substantially greater improvement in pain and function through 4 years.
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Spine
· Jun 2010
Randomized Controlled Trial
Multicenter Study
This was a randomized, double-blind, placebo-controlled clinical trial. ⋯ Duloxetine significantly reduced pain and improved functioning in patients with CLBP. The safety and tolerability were similar to those reported in earlier studies.
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