Spine
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Randomized Controlled Trial
The McKenzie method compared with manipulation when used adjunctive to information and advice in low back pain patients presenting with centralization or peripheralization: a randomized controlled trial.
Randomized controlled trial. ⋯ In patients with low back pain for more than 6 weeks presenting with centralization or peripheralization of symptoms, we found the McKenzie method to be slightly more effective than manipulation when used adjunctive to information and advice.
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Randomized Controlled Trial Comparative Study
Tranexamic acid reduces perioperative blood loss in cervical laminoplasty: a prospective randomized study.
A prospective randomized comparative study. ⋯ TXA significantly reduced perioperative blood loss, primarily through a reduction in postoperative blood loss, in cervical laminoplasty.
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Randomized Controlled Trial Multicenter Study
Polyethylene glycol hydrogel spinal sealant (DuraSeal Spinal Sealant) as an adjunct to sutured dural repair in the spine: results of a prospective, multicenter, randomized controlled study.
A prospective, multicenter, randomized, two-arm, single-blind, investigational device exemption pivotal study. ⋯ The PEG hydrogel spinal sealant evaluated in this study is safe and effective for providing watertight closure when used as an adjunct to sutured dural repair during spinal surgery. This readily available tool is superior to other standard of care technologies commonly used to achieve intraoperative watertight dural closure.
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Randomized Controlled Trial
A randomized, controlled, double-blind trial of fluoroscopic caudal epidural injections in the treatment of lumbar disc herniation and radiculitis.
A randomized, controlled, double-blind trial. ⋯ Caudal epidural injection with local anesthetic with or without steroids might be effective in patients with disc herniation or radiculitis. The present evidence illustrates potential superiority of steroids compared with local anesthetic at 1-year follow-up.