Spine
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Comparative Study
Comparison of Freshly Isolated Adipose Tissue-derived Stromal Vascular Fraction and Bone Marrow Cells in a Posterolateral Lumbar Spinal Fusion Model.
Rat posterolateral lumbar fusion model. ⋯ In a rat model, A-SVF cells yielded a comparable fusion mass volume and radiographic rate of fusion to BMCs when combined with a clinical-grade bone graft substitute. These results suggest the feasibility of using freshly isolated A-SVF cells in spinal fusion procedures.Level of Evidence: N/A.
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Comparative Study
Cervical Alignment Following Posterior Cervical Fusion Surgery: Cervical Pedicle Screw Versus Lateral Mass Screw Fixation.
Retrospective comparative study. ⋯ The present study is the first radiologic comparison of LMS and CPS fixation after posterior-only fusion surgery. CPS resulted in more reliable and well-preserved SA correction, whereas CL and SVA did not differ between the two groups over time due to loss of correction.Level of Evidence: 4.
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Retrospective review of prospectively-collected registry data. ⋯ Although patients with NPP had slightly poorer function and quality of life, all patients experienced a clinically meaningful improvement in patient-reported outcomes, regardless of the predominant pain location. High rates of satisfaction and return-to-work were also achieved. In the context of proper indications, these findings suggest that ACDF can be equally effective for DCR patients with varying combinations of NP or AP.Level of Evidence: 3.
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A longitudinal panel study. ⋯ Previous LBP was associated with LBP 5 years later among survivors of the GEJE. Furthermore, the effect on subsequent LBP was stronger with a higher frequency of previous LBP episodes.Level of Evidence: 3.
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Comparative Study
PLF vs PLIF and the fate of L5-S1: Analysis of Operative Nonunion Rates among 3065 Patients with Lumbar Fusions from a Regional Spine Registry.
A retrospective cohort study with chart review. ⋯ In a large cohort of patients with >4 years of follow-up, we found no difference in operative nonunions between PLF and PLIF except for constructs that included L5-S1 in which the risk of nonunion was limited to PLF patients.Level of Evidence: 3.