Spine
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Comparative Study
Comparison of Freshly Isolated Adipose Tissue-derived Stromal Vascular Fraction and Bone Marrow Cells in a Posterolateral Lumbar Spinal Fusion Model.
Rat posterolateral lumbar fusion model. ⋯ In a rat model, A-SVF cells yielded a comparable fusion mass volume and radiographic rate of fusion to BMCs when combined with a clinical-grade bone graft substitute. These results suggest the feasibility of using freshly isolated A-SVF cells in spinal fusion procedures.Level of Evidence: N/A.
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Multicenter Study Comparative Study
Comparison of 2-level cervical disc replacement vs. 2-level anterior cervical discectomy and fusion in the outpatient setting.
Retrospective cohort study. ⋯ To our knowledge, this is the largest multicenter study examining the safety of two-level outpatient CDR procedures. Outpatient two-level CDR was associated with similarly safe outcomes when compared to inpatient two-level CDR and outpatient two-level ACDF. This suggests that two-level CDR can be performed safely in the outpatient setting.Level of Evidence: 3.
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Comparative Study
Cervical Alignment Following Posterior Cervical Fusion Surgery: Cervical Pedicle Screw Versus Lateral Mass Screw Fixation.
Retrospective comparative study. ⋯ The present study is the first radiologic comparison of LMS and CPS fixation after posterior-only fusion surgery. CPS resulted in more reliable and well-preserved SA correction, whereas CL and SVA did not differ between the two groups over time due to loss of correction.Level of Evidence: 4.
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Retrospective review of prospectively-collected registry data. ⋯ Although patients with NPP had slightly poorer function and quality of life, all patients experienced a clinically meaningful improvement in patient-reported outcomes, regardless of the predominant pain location. High rates of satisfaction and return-to-work were also achieved. In the context of proper indications, these findings suggest that ACDF can be equally effective for DCR patients with varying combinations of NP or AP.Level of Evidence: 3.