Spine
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Multicenter Study Comparative Study
Comparison of 2-level cervical disc replacement vs. 2-level anterior cervical discectomy and fusion in the outpatient setting.
Retrospective cohort study. ⋯ To our knowledge, this is the largest multicenter study examining the safety of two-level outpatient CDR procedures. Outpatient two-level CDR was associated with similarly safe outcomes when compared to inpatient two-level CDR and outpatient two-level ACDF. This suggests that two-level CDR can be performed safely in the outpatient setting.Level of Evidence: 3.
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A longitudinal panel study. ⋯ Previous LBP was associated with LBP 5 years later among survivors of the GEJE. Furthermore, the effect on subsequent LBP was stronger with a higher frequency of previous LBP episodes.Level of Evidence: 3.
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Comparative Study Observational Study
Do Markers of Inflammation and/or Muscle Regeneration in Lumbar Multifidus Muscle and Fat Differ between Individuals with Good or Poor Outcome Following Microdiscectomy for Lumbar Disc Herniation?
Observational study. ⋯ Results show a relationship between impaired muscle regeneration profile in multifidus muscle and poor outcome following microdiscectomy for LDH. Inflammatory dysregulation in subcutaneous fat overlying the back region might predict poor surgical outcome.Level of Evidence: 4.
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Retrospective review of prospectively-collected registry data. ⋯ Although patients with NPP had slightly poorer function and quality of life, all patients experienced a clinically meaningful improvement in patient-reported outcomes, regardless of the predominant pain location. High rates of satisfaction and return-to-work were also achieved. In the context of proper indications, these findings suggest that ACDF can be equally effective for DCR patients with varying combinations of NP or AP.Level of Evidence: 3.
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Comparative Study
Comparison of different Surgical Systems for Treatment of Early Onset Scoliosis in the Context of Release of Titanium Ions.
Case-control study. ⋯ Neverless the system used, the concentration of soluble titanium forms in both ST and blood was only slightly higher than in the control and did not exceed the allowable levels. The increased level of titanium with GGS system is probably associated with the friction between implant components, whereas the components in the other systems are immobile relative to each other.Level of Evidence: 3.