Spine
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A cross-sectional survey of households selected using multistage stratified sampling. ⋯ Chronic spinal pain is a common problem in the Nigerian community, and persons 60 years of age and older may be at particularly elevated risk. Chronic spinal pain is associated with increased probability of comorbid physical and mental disorders. These comorbid conditions partly but do not fully explain the disability associated with chronic spinal pain, which therefore constitutes a substantial health burden on the society.
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Multicenter Study
Predictors of change in postoperative pulmonary function in adolescent idiopathic scoliosis: a prospective study of 254 patients.
A multicenter study of prospectively collected pulmonary function testing and radiographic measures in patients surgically treated for adolescent idiopathic scoliosis (AIS). ⋯ Aside from preoperative PFT values, open anterior approaches predict the largest percent of variance in 2-year PFT. Additionally, a clinically significant reduction in the predicted 2-year pulmonary function is more likely when performing a thoracoplasty. The magnitude of the effects for both these variables, however, is modest. This may facilitate the decision-making process as regards to operative intervention.
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Multicenter Study Comparative Study
Analysis of sagittal alignment in thoracic and thoracolumbar curves in adolescent idiopathic scoliosis: how do these two curve types differ?
Retrospective chart review and radiographic analysis. ⋯ An increased pelvic incidence, associated with both thoracic and thoracolumbar curves when compared with the normal adolescent population, does not appear to be the potential determinant of the development of thoracic versus thoracolumbar scoliosis, but may be a risk factor for the development of adolescent idiopathic scoliosis. The theory of anterior overgrowth may be supported by the identification of thoracic hypokyphosis, despite an increased pelvic incidence and lumbar lordosis, in patients with thoracic scoliosis. The association between sagittal measurements and the etiology of thoracolumbar curve formation is less clear; however, regional anterior overgrowth in the lumbar spine may also be responsible for the deformity.
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Randomized Controlled Trial Multicenter Study
Results of the prospective, randomized, multicenter Food and Drug Administration investigational device exemption study of the ProDisc-L total disc replacement versus circumferential fusion for the treatment of 1-level degenerative disc disease.
A prospective, randomized, multicenter, Food and Drug Administration-regulated Investigational Device Exemption clinical trial. ⋯ ProDisc-L has been found to be safe and efficacious. In properly chosen patients, ProDisc-L has been shown to be superior to circumferential fusion by multiple clinical criteria.
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Multicenter Study
Cervical transforaminal epidural steroid injections: more dangerous than we think?
Survey/case series. ⋯ This study demonstrates a significant risk of serious neurologic injury after cervical TF-ESIs. A growing body of evidence supports an embolic mechanism, whereby inadvertent intra-arterial injection of particulate corticosteroid causes a distal infarct. Embolism to the distal basilar artery region can cause midbrain, pons, cerebellum, thalamus, temporal and occipital lobe infarctions. Other potential mechanisms of infarction include vertebral artery perforation causing dissection/thrombosis and needle-induced vasospasm.