Spine
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Clinical Trial
Superiority of multilevel cervical arthroplasty outcomes versus single-level outcomes: 229 consecutive PCM prostheses.
Class 2 level of evidence: This is a prospective, consecutive series of 229 prosthetic implantations that were concurrently enrolled between single-level versus multilevel cervical arthroplasty comprising an FDA Pilot Study. ⋯ This prospective study of cervical arthroplasty is the first report to date showing significantly improved clinical outcomes for multilevel cervical arthroplasty compared with single-level cervical disc replacement using an FDA validated outcome instrument.
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An experimental study on mechanical allodynia, c-Fos expression, and 200-kDa-neurofilament immunoreactive (IR) afferent expression in the substantia gelatinosa related to compression of dorsal root ganglion (DRG). ⋯ DRG compression induced allodynia and that RT97-IR afferents increased in the superficial dorsal horn of the spinal cord. The increase of RT97-IR afferents may be related to the mechanisms for the observed allodynia.
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Review Case Reports
Combined extraforaminal and intradiscal cement leakage following percutaneous vertebroplasty.
A case report and review of the literature are presented. ⋯ Although considered a minimally invasive procedure, percutaneous vertebroplasty with polymethylmethacrylate is not risk free. Intractable neurologic complications can occur if it is not performed by experienced physicians under appropriate indications and cautionary safeguards.
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Cross-sectional population-based study. ⋯ Consequences of MP show a slightly different pattern for men and women. Women with any MPreport more healthcare use for MP, while men report more work disability due to low back pain only. These sex differences can not be explained by general risk factors, but associations between these factors and consequences of MP show some sex differences.
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Multicenter Study Comparative Study
Analysis of sagittal alignment in thoracic and thoracolumbar curves in adolescent idiopathic scoliosis: how do these two curve types differ?
Retrospective chart review and radiographic analysis. ⋯ An increased pelvic incidence, associated with both thoracic and thoracolumbar curves when compared with the normal adolescent population, does not appear to be the potential determinant of the development of thoracic versus thoracolumbar scoliosis, but may be a risk factor for the development of adolescent idiopathic scoliosis. The theory of anterior overgrowth may be supported by the identification of thoracic hypokyphosis, despite an increased pelvic incidence and lumbar lordosis, in patients with thoracic scoliosis. The association between sagittal measurements and the etiology of thoracolumbar curve formation is less clear; however, regional anterior overgrowth in the lumbar spine may also be responsible for the deformity.