Spine
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Randomized Controlled Trial
The efficacy of rhBMP-2 for posterolateral lumbar fusion in smokers.
Retrospective review of prospectively collected data, as part of an IRB-approved, FDA-regulated, randomized, nonblinded IDE trial of rhBMP-2 matrix for lumbar spinal fusion. ⋯ The results of this study suggest that rhBMP-2 may enhance fusion rate in cigarette smokers undergoing single-level instrumented posterolateral lumbar fusion. Despite the improvement in fusion rate with rhBMP-2, clinical outcomes measures were still adversely affected in smokers.
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Randomized Controlled Trial
Does shaving the incision site increase the infection rate after spinal surgery?
A prospective randomized clinical study. ⋯ The shaving of the incision site immediately before spinal surgery may increase the rate of postoperative infection.
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Cadaveric motion segment experiment. ⋯ The cervical spine has approximately 20% of the bending strength of the lumbar spine but 45% of its compressive strength. This suggests that the neck is relatively vulnerable in bending.
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A prospective study. ⋯ DSA may be a reliable indicator for predicting the spinal residual growth potential in IS patients, but it should be correlated with menarchal status and chronologic ages.