Spine
-
Cross-sectional population-based study. ⋯ Consequences of MP show a slightly different pattern for men and women. Women with any MPreport more healthcare use for MP, while men report more work disability due to low back pain only. These sex differences can not be explained by general risk factors, but associations between these factors and consequences of MP show some sex differences.
-
An experimental study on mechanical allodynia, c-Fos expression, and 200-kDa-neurofilament immunoreactive (IR) afferent expression in the substantia gelatinosa related to compression of dorsal root ganglion (DRG). ⋯ DRG compression induced allodynia and that RT97-IR afferents increased in the superficial dorsal horn of the spinal cord. The increase of RT97-IR afferents may be related to the mechanisms for the observed allodynia.
-
Randomized Controlled Trial Multicenter Study
Results of the prospective, randomized, multicenter Food and Drug Administration investigational device exemption study of the ProDisc-L total disc replacement versus circumferential fusion for the treatment of 1-level degenerative disc disease.
A prospective, randomized, multicenter, Food and Drug Administration-regulated Investigational Device Exemption clinical trial. ⋯ ProDisc-L has been found to be safe and efficacious. In properly chosen patients, ProDisc-L has been shown to be superior to circumferential fusion by multiple clinical criteria.
-
Narrative review. ⋯ Transparency in research methods and clear communication can avoid many of the described pitfalls in outcomes assessment, allowing researchers to advocate appropriately for improvement in patient care.
-
Randomized Controlled Trial
Erector spinae muscle changes on magnetic resonance imaging following lumbar surgery through a posterior approach.
Prospective randomized study of patients undergoing lumbar arthrodesis. ⋯ Erector spinae muscle alterations mainly occur distal to posterior lumbar surgical procedures.