The American journal of emergency medicine
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The digital nerve block is an effective method of anesthesia before minor surgical interventions on the fingers. However, patients may experience a lot of pain and anxiety during this procedure. The efficacy of topical vapocoolant spray during minor procedures has been demonstrated in previous studies. we aimed to evaluate the effectiveness of topical vapocoolant spray in reducing pain during digital nerve block. ⋯ Spray application prior to digital nerve blocking can be used to reduce needle penetration pain associated with this procedure and pain associated with local anesthetic infiltration.
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Out-of-Hospital Cardiac Arrests (OHCA) are one of the biggest challenges facing medical systems world-wide. Each year, more than 420,000 Americans experience cardiac arrests with a survival rate of approximately 10%.1 A large challenge to treating OHCA continues to be rapid access to AEDs which can increase survival rates up to 40%.1 While pivotal to an OHCA patient's survival, AEDs are not always readily available. Advances in unmanned aerial systems (UAS) - commonly referred to as drones - can provide a solution since UAS have the ability to rapidly carry an AED payload to an emergency site. ⋯ Drone response time was significantly faster than ground EMS response by a factor of 5× (P value < .05). Drones were able to get to the incident scene of a theoretical OHCA faster without and with vertical response challenges. The results show that UAS delivery of AEDs is not only possible in the Charlottesville-Albemarle County area, but an effective way to decrease response time to improve chances of survival for a person experiencing an OHCA in similar suburban areas.
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Randomized Controlled Trial Multicenter Study Comparative Study
A comparative study of dexmedetomidine and propofol to prevent recovery agitation in adults undergoing procedural sedation with ketamine: A randomized double-blind clinical trial.
The present study was designed to evaluate the effect of dexmedetomidine and propofol on ketamine-induced recovery agitation in adults when used as co-administration with ketamine. ⋯ In this study, a combination of ketamine-dexmedetomidine and ketamine-propofol reduced the incidence and severity of ketamine-induced recovery agitation in adults undergoing procedural sedation in the ED.
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Review Meta Analysis
Efficacy of intravenous vitamin C intervention for septic patients: A systematic review and meta-analysis based on randomized controlled trials.
The role of vitamin C in sepsis is still controversial, we aimed to systematically review the efficacy of intravenous vitamin C supplementation in the treatment of sepsis. ⋯ Based on current RCTs, our work indicated that mono-intravenous vitamin C therapy may reduce short-term mortality of sepsis patients, and it may protect organ functions. Due to the limitation of the quantity and quality of included studies, the above conclusions need to be verified by more large scale and high quality randomized control trials.
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Review Meta Analysis
Efficacy and safety of tranexamic acid in aneurysmal subarachnoid hemorrhage: A meta-analysis of randomized controlled trials.
Tranexamic acid, as a traditional hemostatic agent, is commonly used to treat or prevent excessive blood loss. However, the role of tranexamic acid in promoting good clinical outcomes and reducing mortality and risk of adverse events during the treatment of aneurysmal subarachnoid hemorrhage remains unclear. ⋯ These findings indicate that the routine use of tranexamic acid is not suggested for patients with aneurysmal subarachnoid hemorrhage.