The American journal of emergency medicine
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Meta Analysis
Premorbid angiotensin converting enzyme inhibitors or angiotensin II receptor blockers in patients with sepsis.
The aim of this study was to conduct a systematic review and meta-analysis to investigate the effect of the premorbid use of angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers (ACEI/ARB) on short-term mortality in patients with sepsis. ⋯ In this meta-analysis, the premorbid ACEI/ARB was associated with significantly lower short-term mortality in patients with sepsis despite the significantly higher risk of AKI.