The American journal of emergency medicine
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Am J Emerg Med
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Eperisone hydrochloride is a centrally acting muscle relaxant prescribed for muscle stiffness that acts by depressing the activities of α and γ efferent neurons in the spinal cord and supraspinal structures. Although a case of eperisone-induced severe QT prolongation had been reported, the relationship between serum eperisone concentration and QT interval remains obscure. ⋯ Serum eperisone concentration correlates with QTc interval in patients who overdose on eperisone.