Resuscitation
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Review Meta Analysis
When should chest compressions be paused to analyze the cardiac rhythm?: A systematic review and meta-analysis.
Most guidelines recommend pausing chest compressions at 2 min intervals to analyze the cardiac rhythm. We conducted a systematic review and meta-analysis to define the optimal interval at which to pause chest compressions in adults for cardiac rhythm analysis in any setting. ⋯ There is a paucity of quality evidence to support pausing chest compressions at any singular interval to assess the cardiac rhythm in adults in cardiac arrest in any setting. Very low-quality evidence suggests improved clinical outcomes in patients receiving 200-compression intervals compared with 1- or 3 min intervals.
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Review Meta Analysis
The association of gasping and outcome, in out of hospital cardiac arrest: A systematic review and meta-analysis.
Gasping is common after cardiac arrest, and its frequency decreases over time. The aim of this study was to conduct a meta-analysis to evaluate the association of gasping and survival to discharge in patients who suffered out-of-hospital cardiac arrest. ⋯ Findings of this meta-analysis demonstrated that gasping is common after cardiac arrest, and is associated with increased survival to discharge. Patients who are cardiac arrest with gasping should be promptly resuscitated.
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Randomized Controlled Trial Multicenter Study
Variability in Quality of Chest Compressions Provided During Simulated Cardiac Arrest Across Nine Pediatric Institutions.
The variability in quality of CPR provided during cardiac arrest across pediatric institutions is unknown. We aimed to describe the degree of variability in the quality of CPR across 9 pediatric institutions, and determine if variability across sites would be affected by Just-in-Time CPR training and/or visual feedback during simulated cardiac arrest. ⋯ The quality of CPR across multiple pediatric institutions is variable. Variability in CPR quality across institutions persists even with the implementation of a Just-in-Time training session and visual feedback for CPR quality during simulated cardiac arrest.
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Randomized Controlled Trial Multicenter Study
Anxiety and depression among out-of-hospital cardiac arrest survivors.
Survivors of out-of-hospital cardiac arrest (OHCA) may experience psychological distress but the actual prevalence is unknown. The aim of this study was to investigate anxiety and depression within a large cohort of OHCA-survivors. ⋯ One fourth of OHCA-survivors reported symptoms of anxiety and/or depression at 6 months which was similar to STEMI-controls and previous normative data. Subjective cognitive problems were associated with an increased risk for psychological distress. Since psychological distress affects long-term prognosis of cardiac patients in general it should be addressed during follow-up of survivors with OHCA due to a cardiac cause. ClinicalTrials.gov NCT01020916/NCT01946932.
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Randomized Controlled Trial
Chest compression fraction: A time dependent variable of survival in shockable out-of-hospital cardiac arrest.
The role of chest compression fraction (CCF) in resuscitation of shockable out-of-hospital cardiac arrest (OHCA) is uncertain. We evaluated the relationship between CCF and clinical outcomes in a secondary analysis of the Resuscitation Outcomes Consortium PRIMED trial. ⋯ In this study of OHCA patients presenting in a shockable rhythm, CCF was paradoxically associated with lower odds of survival. CCF is a complex measure and taken by itself may not be a consistent predictor of good clinical outcomes.