Journal of pain and symptom management
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J Pain Symptom Manage · Jan 1998
Case ReportsHigh-dose intrathecal morphine to control cancer pain--a case report.
A 52-year-old woman with recurrent parotid gland cancer was referred to our hospital for uncontrollable severe pain in her right leg. We implanted a port in the chest wall and started a morphine infusion into the intrathecal space. ⋯ Cerebrospinal fluid was noted at the site of puncture and spinal catheter implantation. We removed the port and intrathecal catheter, then implanted the port again on the other side of the chest wall.
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J Pain Symptom Manage · Jan 1998
Randomized Controlled Trial Comparative Study Clinical TrialEfficacy of senna versus lactulose in terminal cancer patients treated with opioids.
The best laxative for terminal cancer patients treated with opioids still remains to be determined. This comparative study was conducted with the objective of determining treatment and cost efficiency for senna and lactulose in terminal cancer patients treated with opioids. The methodology used a randomized, open, parallel group design. ⋯ No difference was found between the laxatives in defecation-free intervals or in days with defecation. The final scores for general health status were similar in both groups. Given that the two treatments have similar efficacy and adverse effects, a recommendation is made for the use of senna because its cost is lower than lactulose.