Journal of pain and symptom management
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J Pain Symptom Manage · Aug 2014
Multicenter Study Comparative StudyComparative effectiveness of senna to prevent problematic constipation in pediatric oncology patients receiving opioids: a multicenter study of clinically detailed administrative data.
Pediatric oncology patients often receive prolonged courses of opioids, which can result in constipation. ⋯ Initiating senna therapy, compared with other oral bowel medications, diminishes the subsequent risk of surrogate markers of problematic constipation in this population.