Journal of pain and symptom management
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J Pain Symptom Manage · Feb 2018
Randomized Controlled Trial Multicenter StudyResults of a Double-Blind, Randomized, Placebo-Controlled Study of Nabiximols Oromucosal Spray as Adjunctive Therapy in Advanced Cancer Patients With Chronic Uncontrolled Pain.
Prior Phase 2/3 studies found that cannabinoids might provide adjunctive analgesia in advanced cancer patients with uncontrolled pain. ⋯ Nabiximols might have utility in patients with advanced cancer who receive a lower opioid dose, such as individuals with early intolerance to opioid therapy.
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J Pain Symptom Manage · Feb 2018
Randomized Controlled TrialWhich physicians' behaviors on death pronouncement affect family-perceived physician compassion? A randomized, scripted, video-vignette study.
Although the death of a loved one is a devastating family event, little is known about which behaviors positively affect families' perceptions on death pronouncements. ⋯ To convey compassion on death pronouncement, we recommend that physicians initiate prompt examination, explain that the physician has received a sign-out, perform examination respectfully, ascertain the time of death with a wristwatch, and reassure the families that the patient did not experience pain.