Journal of critical care
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Journal of critical care · Jun 2018
Review Meta AnalysisReduced circulating B cells and plasma IgM levels are associated with decreased survival in sepsis - A meta-analysis.
B cell function and antibody production are crucial factors in host protection during inflammation. We aimed to synthesize the available evidence on the association between the reduction of circulating B cells and plasma immunoglobulin (IgM) levels and decreased survival during sepsis. ⋯ The protocol was registered (PROSPERO 2016:CRD42016053184).
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Journal of critical care · Jun 2018
Dead space analysis at different levels of positive end-expiratory pressure in acute respiratory distress syndrome patients.
To analyze the effects of positive end-expiratory pressure (PEEP) on Bohr's dead space (VDBohr/VT) in patients with acute respiratory distress syndrome (ARDS). ⋯ Increases in PEEP result in higher VDBohr/VT only when associated with an increase in driving pressure.
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Journal of critical care · Jun 2018
Early nutritional inadequacy is associated with psoas muscle deterioration and worse clinical outcomes in critically ill surgical patients.
To explore whether psoas cross sectional area (CSA) and density (Hounsfield Units, HU) are associated with nutritional adequacy and clinical outcomes in surgical intensive care unit patients. ⋯ In this exploratory study, early nutritional deficits were correlated with muscle quality deterioration. Inpatient gain in psoas density, compared to maintenance or loss, is associated with shorter hospital stay.
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Journal of critical care · Jun 2018
Hemoglobin thresholds and red blood cell transfusion in adult patients with moderate or severe traumatic brain injuries: A retrospective cohort study.
We aimed to evaluate the association between transfusion practices and clinical outcomes in patients with traumatic brain injury. ⋯ During ICU stay, transfused patients tended to have lower Hb levels and worse outcomes than patients who did not receive RBCs, after adjustment for confounders.