Journal of critical care
-
Journal of critical care · Jun 2018
Randomized Controlled TrialA pilot trial of l-carnitine in patients with traumatic brain injury: Effects on biomarkers of injury.
To investigate the effects of l-Carnitine on neuron specific enolase (NSE) as a marker of inflammation in patients with traumatic brain injury (TBI). ⋯ We concluded that despite improvements in neurobehavioral function and the degree of cerebral edema, 7-days of treatment with l-Carnitine failed to reduce serum NSE levels or improve mortality rate at 90days in patients with TBI.