Journal of critical care
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Journal of critical care · Jun 2018
Review Meta AnalysisReduced circulating B cells and plasma IgM levels are associated with decreased survival in sepsis - A meta-analysis.
B cell function and antibody production are crucial factors in host protection during inflammation. We aimed to synthesize the available evidence on the association between the reduction of circulating B cells and plasma immunoglobulin (IgM) levels and decreased survival during sepsis. ⋯ The protocol was registered (PROSPERO 2016:CRD42016053184).