Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial Clinical Trial
Fasciculations, myalgia and biochemical changes following succinylcholine with atracurium and lidocaine pretreatment.
To determine the attenuation in the incidence of myalgia, fasciculations and changes in serum potassium and creatinine kinase concentrations when atracurium and lidocaine were used in combination and separately as pretreatment before succinylcholine. ⋯ Atracurium and lidocaine individually reduce postoperative myalgia, with further decrease occurring when used together.
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Randomized Controlled Trial Clinical Trial
Granisetron reduces postoperative nausea and vomiting throughout menstrual cycle.
The incidence of postoperative nausea and vomiting (PONV) is influenced by menstruation. This study was undertaken to assess the efficacy of granisetron, a selective 5-hydroxytryptamine type 3 receptor antagonist, for preventing PONV in patients during two different phases of menstrual cycle. ⋯ Granisetron was effective in reducing the incidence of PONV in both phases of the menstrual cycle studied.
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Randomized Controlled Trial Clinical Trial
Postoperative analgesia with i.v. propacetamol and ketoprofen combination after disc surgery.
The concept of balanced analgesia suggests that a combination of analgesic drugs may enhance analgesia and reduce side effects after surgery. This study evaluated the effect of the combination of propacetamol (Prodafalgan) and ketoprofen (Profenid) after surgery of a herniated disc of the lumbar spine. ⋯ The combination of propacetamol and ketoprofen reduced pain scores both at rest and on movement. The drug combination did not reduce the morphine consumption and incidence of side effects.