Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Significant pulmonary hypertension is a predictor of postoperative right heart insufficiency and increased mortality in patients undergoing orthotopic heart transplantation. Since the use of iv vasodilators is limited by their systemic effects, we evaluated the pulmonary and systemic hemodynamic effects of inhaled aerosolized iloprost (IP) in heart transplant candidates with elevated pulmonary vascular resistance (PVR). ⋯ Inhaled aerosolized iloprost effectively reduces MPAP and is accompanied by an increase in CI and stroke index. Further advantages of iloprost inhalation are the lack of adverse reactions and ease of administration. Iloprost may be a useful drug to screen for vascular reactivity in cardiac transplantation patients.
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Randomized Controlled Trial Multicenter Study Clinical Trial
P6 acupressure may relieve nausea and vomiting after gynecological surgery: an effectiveness study in 410 women.
To investigate the effect of sensory stimulation of the P6 point on postoperative nausea and vomiting (PONV) after gynecological surgery in the everyday clinical setting (effectiveness study). ⋯ P6 acupressure is a non-invasive method that may have a place as prophylactic antiemetic therapy during gynecological surgery.
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Randomized Controlled Trial Clinical Trial
Metoclopramide decreases emesis but increases sedation in tramadol patient-controlled analgesia.
To evaluate the clinical benefits and disadvantages of adding metoclopramide to tramadol for patient-controlled analgesia (PCA). ⋯ The incidence and severity of nausea/vomiting decreased if metoclopramide was added to tramadol for PCA. An increased incidence of sedation was noticed with this drug combination.
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Randomized Controlled Trial Clinical Trial
In children, nitrous oxide decreases pain on injection of propofol mixed with lidocaine.
To investigate if 50% nitrous oxide reduces the pain during injection of propofol mixed with lidocaine in children. ⋯ Nitrous oxide reduces pain during induction with propofol mixed with lidocaine in healthy children.