Nutrition
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Review Meta Analysis
Soy isoflavone supplementation could reduce body weight and improve glucose metabolism in non-Asian postmenopausal women--a meta-analysis.
The objective of this study was to conduct a systematic review and a meta-analysis to confirm the effects of soy isoflavone supplementation on body weight, fasting glucose, and insulin level in non-Asian postmenopausal women. ⋯ This meta-analysis showed soy isoflavone supplementation could be beneficial for body weight reduction, glucose, and insulin control in plasma. Large and well-designed studies are recommended to confirm this conclusion.
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Review Meta Analysis
Soy isoflavone supplementation could reduce body weight and improve glucose metabolism in non-Asian postmenopausal women--a meta-analysis.
The objective of this study was to conduct a systematic review and a meta-analysis to confirm the effects of soy isoflavone supplementation on body weight, fasting glucose, and insulin level in non-Asian postmenopausal women. ⋯ This meta-analysis showed soy isoflavone supplementation could be beneficial for body weight reduction, glucose, and insulin control in plasma. Large and well-designed studies are recommended to confirm this conclusion.
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Malnutrition continues to be under-recognized and undertreated in the hospitalized setting. Although no "gold standard" for the diagnosis of malnutrition exists, the Subjective Global Assessment (SGA) is a commonly used malnutrition assessment tool. The study aim was to explore the reporting of inter-rater reliability (IRR) of the SGA when used as a nutritional assessment tool in the published literature. ⋯ The IRR is rarely reported in the published literature and has not yet been reported across experience levels.
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Diabetic macular edema and retinopathy are low-grade inflammatory conditions. Infusions of antitumor necrosis factor-α (anti-TNF-α) antibody and antivascular endothelial growth factor (anti-VEGF) antibody have been shown to be at least partly effective in the treatment of diabetic macular edema and proliferative diabetic retinopathy. Intravitreal therapy of diabetic macular edema by the anti-TNF-α antibody has been found to produce significant side effects and anti-VEGF therapy to be ineffective. ⋯ The retina is rich in polyunsaturated fatty acids, especially in ω-3, and several studies have shown that polyunsaturated fatty acids prevent diabetic retinopathy. Lipoxins, resolvins, and protectins derived from various polyunsaturated fatty acids possess anti-inflammatory actions and suppress the production of interleukin-6, and TNF-α and VEGF have antiangiogenic actions. In view of these evidences, I propose that lipoxins, resolvins, and protectins could be of significant benefit in the prevention and management of diabetic macular edema and retinopathy.
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Muscle disuse is often observed after injury or during periods of illness, resulting in the loss of muscle mass and strength, with sometimes debilitating consequences. Although substantial advancements have been made in determining the mechanisms responsible for the etiology of muscle disuse atrophy in rodents, only in recent years have studies of any significant number focused on reaffirming these findings in humans. In this review, we discuss the processes responsible for disuse atrophy as based on current evidence and highlight where gaps in our knowledge persist. Furthermore, given the emphasis placed on resistance exercise and nutrition as potential therapeutic countermeasures, we consider recent advancements in the study of resistance exercise and nutrition in the stimulation of muscle protein synthesis and the associated implications when devising effective treatment strategies.