Nutrition
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Randomized Controlled Trial Multicenter Study
Palmitoylethanolamide and polydatin in pediatric irritable bowel syndrome: A multicentric randomized controlled trial.
This study aimed to evaluate the efficacy and safety of co-micronized palmitoylethanolamide (PEA)/polydatin (PD) in the treatment of abdominal pain symptoms in pediatric patients with irritable bowel syndrome (IBS). ⋯ Co-micronized PEA/PD is a safe and effective treatment to treat abdominal pain symptoms in pediatric IBS.