Nutrition
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Radical resection combined with prophylactic hyperthermic intraperitoneal chemotherapy (p-HIPEC) is a promising treatment for locally advanced gastric cancer (LAGC), though factors influencing its long-term benefits remain unclear. This study aimed to assess the impact of computed tomography (CT)-based body composition parameters on survival in patients undergoing this combination treatment, exploring nutritional factors affecting long-term survival and developing a prognostic model. ⋯ Body composition and tumor characteristics are independent predictors of overall survival in LAGC patients. Nomograms integrating these factors provide reliable prognostic predictions.
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Celiac disease (CD) presents formidable challenges, requiring rigorous adherence to a gluten-free diet (GFD) AIM: In this study we probed the impact of GFD on depression in people with CD, analyzing depression prevalence across diverse backgrounds and scrutinizing the distribution of macro- and micronutrients. ⋯ This study delved into the intricate interplay of dietary, mental health, and CD factors, furnishing comprehensive insights and a holistic framework for optimal management strategies for CD patients.
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Gut microbiota dysbiosis plays a critical role in malnutrition caused by food intolerance and intestinal inflammation in children, which needs to be addressed. We assessed the efficacy and safety of washed microbiota transplantation (WMT) for gastrointestinal disease-related malnourished children. ⋯ This study indicated that WMT might be effective and safe for improving nutritional status and gastrointestinal symptoms in gastrointestinal disease-related malnourished children at 3-mo follow-up. WMT was expected to be a new therapeutic option for these patients.