Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study
Comparison of analgesic efficacy of paracetamol and tramadol for pain relief in active labor.
To evaluate the efficacy and safety profile of paracetamol in comparison with tramadol for pain relief during active labor. ⋯ Intravenous paracetamol provides comparable analgesia as intramuscular tramadol during active labor.
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A 35-year-old man had symptomatic hyperammonemia and normal liver function after repeat kidney transplantation. He presented with gastrointestinal symptoms, which quickly progressed to altered mental status. ⋯ Urine acids and serum organic acids were not diagnostic of any urea cycle disorder. Histology did not reveal a clear etiology for the hyperammonemia.
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Acute kidney injury is a frequent complication in the intensive care unit that is associated with increased mortality and morbidity. Traditional models consider reductions of global renal blood flow as the cause of acute kidney injury. However, a complex interplay between ischemia-reperfusion injury and inflammation may lead to intrarenal hypoperfusion and acute kidney injury. The role of changes of global renal blood flow as a cause for acute kidney injury remains controversial, especially in sepsis-induced acute kidney injury.
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Randomized Controlled Trial
Effect of hydroxyethyl starch 130/0.4 on ischemia-reperfusion determinants in minor lower extremity surgery with tourniquet application.
To investigate the effect of 6% hydroxyethyl starch (HES) (130/0.4) infusion on ischemia-reperfusion determinants in minor lower extremity operations with tourniquet application. ⋯ HES infusion may be beneficial for reduction of tourniquet-associated ischemia-reperfusion injury; however, further large-scale studies are needed to fully elucidate its mechanism.