BMJ : British medical journal
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Rapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine.
To compare two widely used drug treatments for people with aggression or agitation due to mental illness. ⋯ Both treatments were effective. Midazolam was more rapidly sedating than haloperidol-promethazine, reducing the time people are exposed to aggression. Adverse effects and resources to deal with them should be considered in the choice of the treatment.
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Randomized Controlled Trial Clinical Trial
Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea.
To determine the efficacy of oral morphine in relieving the sensation of breathlessness in patients in whom the underlying aetiology is maximally treated. ⋯ Sustained release, oral morphine at low dosage provides significant symptomatic improvement in refractory dyspnoea in the community setting.