BMJ : British medical journal
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Multicenter Study
β blockers and mortality after myocardial infarction in patients without heart failure: multicentre prospective cohort study.
To assess the association between early and prolonged β blocker treatment and mortality after acute myocardial infarction. ⋯ Early β blocker use was associated with reduced 30 day mortality in patients with acute myocardial infarction, and discontinuation of β blockers at one year was not associated with higher five year mortality. These findings question the utility of prolonged β blocker treatment after acute myocardial infarction in patients without heart failure or left ventricular dysfunction.Trial registration Clinical trials NCT00673036.
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Letter Multicenter Study
Management of prisoners with autism is not perfect but is improving.
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Multicenter Study Comparative Study Observational Study
Prevalence of microcephaly in Europe: population based study.
To provide contemporary estimates of the prevalence of microcephaly in Europe, determine if the diagnosis of microcephaly is consistent across Europe, and evaluate whether changes in prevalence would be detected using the current European surveillance performed by EUROCAT (the European Surveillance of Congenital Anomalies). ⋯ EUROCAT could detect increases in the prevalence of microcephaly from the Zika virus of a similar magnitude to those observed in Brazil. Because of the rarity of microcephaly and discrepant diagnostic criteria, however, the smaller increases expected in Europe would probably not be detected. Clear diagnostic criteria for microcephaly must be adopted across Europe.