BMJ : British medical journal
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Review Meta Analysis
Effect of BCG vaccination against Mycobacterium tuberculosis infection in children: systematic review and meta-analysis.
To determine whether BCG vaccination protects against Mycobacterium tuberculosis infection as assessed by interferon γ release assays (IGRA) in children. ⋯ BCG protects against M tuberculosis infection as well as progression from infection to disease.Trial registration PROSPERO registration No CRD42011001698 (www.crd.york.ac.uk/prospero/).
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Review Meta Analysis Comparative Study
Safety, effectiveness, and cost effectiveness of long acting versus intermediate acting insulin for patients with type 1 diabetes: systematic review and network meta-analysis.
To examine the safety, effectiveness, and cost effectiveness of long acting insulin for type 1 diabetes. ⋯ PROSPERO CRD42013003610.
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Review Meta Analysis
Screening women for intimate partner violence in healthcare settings: abridged Cochrane systematic review and meta-analysis.
To examine the effectiveness of screening for intimate partner violence conducted within healthcare settings to determine whether or not screening increases identification and referral to support agencies, improves women's wellbeing, decreases further violence, or causes harm. ⋯ Though screening is likely to increase identification of intimate partner violence in healthcare settings, rates of identification from screening interventions were low relative to best estimates of prevalence of such violence. It is uncertain whether screening increases effective referral to supportive agencies. Screening does not seem to cause harm in the short term, but harm was measured in only one study. As the primary studies did not detect improved outcomes for women screened for intimate partner violence, there is insufficient evidence for screening in healthcare settings. Studies comparing screening versus case finding, or screening in combination with therapeutic intervention for women's long term wellbeing, are needed to inform the implementation of identification policies in healthcare settings.
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Review Meta Analysis
Long term maintenance of weight loss with non-surgical interventions in obese adults: systematic review and meta-analyses of randomised controlled trials.
To systematically review and describe currently available approaches to supporting maintenance of weight loss in obese adults and to assess the evidence for the effectiveness of these interventions. ⋯ Behavioural interventions that deal with both diet and physical activity show small but significant benefits on weight loss maintenance.
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Review Meta Analysis
Comparative effectiveness of long term drug treatment strategies to prevent asthma exacerbations: network meta-analysis.
To determine the comparative effectiveness and safety of current maintenance strategies in preventing exacerbations of asthma. ⋯ Strategies with combined inhaled corticosteroids and long acting β agonists are most effective and safe in preventing severe exacerbations of asthma, although some heterogeneity was observed in this network meta-analysis of full text reports.