BMJ : British medical journal
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Randomized Controlled Trial Multicenter Study
Efficacy of anti-inflammatory or antibiotic treatment in patients with non-complicated acute bronchitis and discoloured sputum: randomised placebo controlled trial.
To evaluate the efficacy of oral anti-inflammatory or antibiotic treatment compared with placebo in the resolution of cough in patients with uncomplicated acute bronchitis and discoloured sputum. ⋯ No significant differences were observed in the number of days with cough between patients with uncomplicated acute bronchitis and discoloured sputum treated with ibuprofen, amoxicillin-clavulanic acid, or placebo.
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Multicenter Study Comparative Study
Effect of socioeconomic disparities on incidence of dementia among biracial older adults: prospective study.
To examine whether observed differences in dementia rates between black and white older people living in the community could be explained by measures of socioeconomic status (income, financial adequacy, education, and literacy) and health related factors. ⋯ These findings suggest that differences in the burden of risk factors, especially socioeconomic status, may contribute to the higher rates of dementia seen among black compared with white older people. Strategies aimed at reducing these disparities may favorably affect the incidence of dementia.
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Randomized Controlled Trial Multicenter Study Comparative Study
Clinical effectiveness of collaborative care for depression in UK primary care (CADET): cluster randomised controlled trial.
To compare the clinical effectiveness of collaborative care with usual care in the management of patients with moderate to severe depression. ⋯ Collaborative care has persistent positive effects up to 12 months after initiation of the intervention and is preferred by patients over usual care.
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Randomized Controlled Trial Multicenter Study Pragmatic Clinical Trial
Clinical effectiveness of a manual based coping strategy programme (START, STrAtegies for RelaTives) in promoting the mental health of carers of family members with dementia: pragmatic randomised controlled trial.
To assess whether a manual based coping strategy compared with treatment as usual reduces depression and anxiety symptoms in carers of family members with dementia. ⋯ A manual based coping strategy was effective in reducing affective symptoms and case level depression in carers of family members with dementia. The carers' quality of life also improved.
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Randomized Controlled Trial Multicenter Study
Impact of wound edge protection devices on surgical site infection after laparotomy: multicentre randomised controlled trial (ROSSINI Trial).
To determine the clinical effectiveness of wound edge protection devices in reducing surgical site infection after abdominal surgery. ⋯ Wound edge protection devices do not reduce the rate of surgical site infection in patients undergoing laparotomy, and therefore their routine use for this role cannot be recommended.