Medical principles and practice : international journal of the Kuwait University, Health Science Centre
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One of the most important side effects of opioids is their influence on the electrical activity of the heart. This review focusses on the effects of opioids on QT interval prolongation and their arrhythmogenic liability. ⋯ The cardiac arrhythmogenicity of various opioids is different. Methadone has a higher capability to induce long QT interval and dangerous arrhythmias in conventional doses than others. To reduce of arrhythmogenic risk, high doses of opioids must be used cautiously with periodic monitoring of ECG in high-risk consumers such as patients under opioid maintenance treatment.
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This study aims to improve the management quality of chronic obstructive pulmonary disease (COPD) in rural areas. ⋯ Doctors can improve the quality of life of patients with COPD and reduce the number of rehospitalizations through use of the network consulting room.
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Rare variants in the TREM2 gene have been reported to significantly increase the risk of Alzheimer's disease in Caucasian populations. Hitherto, this association was not studied in North African populations. In this work, we aimed to study the association between TREM2 exon 2 variants and the risk of late-onset Alzheimer's disease (LOAD) in a Tunisian population. ⋯ These findings do not support a major role for TREM2 in the pathogenesis of LOAD in the Tunisian population.
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To investigate the relationship between serum values of magnesium and the parameters of the pulmonary function tests (PFT) in patients with chronic asthma. ⋯ In this study, hypomagnesemia and hypophosphatemia were found to be the most common electrolyte abnormalities in patients with chronic stable asthma. FEV1, FEV1%, PEF, and PEF% were significantly lower in asthmatic patients with hypomagnesemia compared to asthmatic patients with normomagnesemia.
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Case Reports
Focal Encephalitis, Meningitis, and Acute Respiratory Distress Syndrome Associated with Influenza A Infection.
To present a case of influenza A infection complicated with focal encephalitis, meningitis, and acute respiratory distress syndrome. ⋯ This case report highlights focal encephalitis with concomitant pulmonary complications after influenza A infection.