Journal of anesthesia
-
To determine the accuracy of the bibliographic citations in theJournal of Anesthesia, all references appearing the years 1987 (Vol. 1;n=548) and 1994 (Vol. 8;n=1839) were sequentially numbered and 100 references from each year were randomly selected. After citations of non-journal articles were excluded (n=8 in 1987;n=7 in 1994), the remaining 185 citations were scrutinized. The authors' names, article title, journal title, volume number, page numbers, and year were examined for each reference. ⋯ No significant differences existed in the error rate between the two years. We have demonstrated a considerable level of citation error in the reference lists of theJournal of Anesthesia articles, and no improvement over the last seven years. We recommend that contributors to theJournal of Anesthesia should carefully check the accuracy of their reference listings.
-
Journal of anesthesia · Dec 1995
Inhibitory effect of prostaglandin E1 on gastric secretion during general anesthesia in humans.
The present study was undertaken to clarify the effects of prostaglandin E1 (PGE1) on gastric secretion during general anesthesia. Thirty-three patients, 16 with (PGE1 group) and 17 without (control group) PGE1 administration, scheduled for selective surgery were studied during general anesthesia with nitrous oxide (67%) and enflurane (1%-2% inspired). PGE1 was administered at a rate of 50-200 ng·kg(-1)·min(-1) when hypotensive medication was required. ⋯ The pH of gastric juice increased significantly, and the acidity and pepsin activity decreased after the beginning of the administration of PGE1, and these changes were observed even 1h after discontinuation. There was significant differences in the pH, acidity, and pepsin activity between the two groups after administration of PGE1. The results indicate that PGE1 inhibits gastric secretion at doses that produce a sufficient hypotensive effect under general anesthesia.
-
Journal of anesthesia · Dec 1995
Relationship between plasma neutrophil elastase and respiratory index of patients who had undergone cardiac surgery with cardiopulmonary bypass.
To evaluate the effects of cardiopulmonary bypass (CPB) on the release of polymorphonuclear leukocyte elastase (PMN-E) and postoperative pulmonary function, the perioperative plasma levels of PMN-E in α1-antitrypsin complex (EAC) and hydrogen peroxide concentration in the expired breath were measured in eight patients who underwent cardiac surgery with CPB, and the relationship between EAC levels and the respiratory index (RI) was studied. Although PMN, EAC, and the ratio of EAC to neutrophil (E/N) were elevated significantly after surgery, alveolar-arterial oxygen difference (A-aDO2) and respiratory index (A-aDO2/PaO2) did not change when compared with those of the preoperative period. ⋯ However, there was a significant positive correlation between E/N ratio and respiratory index (r=0.67,P<0.01). Thus excessive release of PMN-E during CPB may be implicated in the etiology of postoperative respiratory dysfunction.