Journal of anesthesia
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Journal of anesthesia · Jan 2009
Bispectral index during epidural puncture predicts anterograde amnesia in patients given midazolam premedication.
We hypothesized anterograde amnesia could be predicted by the bispectral index (BIS) during epidural puncture in patients premedicated with intramuscular midazolam. ⋯ BIS assessment during epidural puncture is informative for the anesthesiologist to predict amnesia following midazolam premedication.
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Although it has been generally believed that parturients have delayed gastric emptying during anesthesia, the most recent reports suggest that gastric emptying is not delayed during pregnancy except during labor. Electrical slow waves in the stomach determine the frequency and the peristaltic nature of gastric contractions. In this study we performed electrogastrography during and after elective cesarean section (CS) in an attempt to evaluate gastric motility. ⋯ Electrogastrography analysis suggests that the frequency of gastric contractions during CS was less than that in the postpartum period.
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Journal of anesthesia · Jan 2009
Desflurane induces airway contraction mainly by activating transient receptor potential A1 of sensory C-fibers.
We previously reported that desflurane induced airway contraction via antidromic tachykinin release from sensory C-fibers. Here, we investigated the effect of desflurane on airway lung resistance (R(L)) using specific receptor antagonists in C-fibers. Young guinea pigs were anesthetized and their tracheas were cannulated with an endotracheal tube via a tracheotomy. ⋯ HC030031 completely inhibited both the first and the second contractile responses induced by desflurane, whereas BCTC had little effect. MEN-10376 also significantly and substantially diminished the contractile response. Desflurane contracts the airway in untreated guinea pigs mainly by activating irritant gas receptor TRPA1 of afferent C-fibers, resulting in the release of contractile tachykinins such as neurokinin A.