Respiratory medicine
-
Respiratory medicine · Dec 2012
Randomized Controlled TrialAssessing efficacy of indacaterol in moderate and severe COPD patients: a 12-week study in an Asian population.
This post hoc analysis evaluated the efficacy of indacaterol, a novel inhaled once-daily long-acting β(2)-agonist, by disease severity (GOLD 2005) in patients with moderate-to-severe COPD from six Asian countries/areas (Hong Kong, India, Japan, Korea, Singapore, Taiwan). ⋯ NCT00794157.
-
Respiratory medicine · Dec 2012
Randomized Controlled TrialWalking exercise response to bronchodilation in mild COPD: a randomized trial.
Patients with mild chronic obstructive pulmonary disease (COPD) present abnormal ventilatory mechanics during exercise and may require bronchodilator therapy. However, bronchodilation does not enhance cycling exercise tolerance in these patients whereas walking may be more sensitive to the effects of bronchodilation. ⋯ Bronchodilation did not improve walking endurance in patients with mild COPD despite small physiological benefits of uncertain clinical relevance.