Allergologia et immunopathologia
-
Allergol Immunopathol (Madr) · May 2015
Randomized Controlled TrialA neglected cause for chronic spontaneous urticaria in children: Helicobacter pylori.
The aetiology of chronic urticaria is usually considered idiopathic. There is a paucity of research both on the prevalence of Helicobacter pylori infection in the aetiology of chronic spontaneous urticaria (CU) in children and also on which patients H. pylori should be investigated. ⋯ In the current study we found that H. pylori is common among children with CU, particularly after eight years of age. We suggest that CU patients with an unknown aetiology should be routinely screened for H. pylori even if they do not present with GI symptoms and that those with H. pylori-positive results may receive treatment.
-
Allergol Immunopathol (Madr) · Mar 2006
Randomized Controlled Trial Comparative StudyEffectiveness of nebulized furosemide added to nebulized salbutamol in children with acute asthma.
Nebulized furosemide has been shown to be protective against bronchoconstricting stimuli. ⋯ Adding nebulized furosemide to nebulized salbutamol in pediatric patients experiencing an acute asthma attack did not produce greater improvement in clinical (p = 0.3829) or spirometric (p = 0.3839) parameters than nebulized salbutamol alone.
-
Allergol Immunopathol (Madr) · Mar 1997
Randomized Controlled Trial Comparative Study Clinical TrialComparative study of inhaled amiloride and inhaled furosemide in exercise-induced asthma.
Certain diuretics such as furosemide, when inhaled, have been found to be useful in preventing Exercise-Induced Asthma (EIA). ⋯ Amiloride is not useful to protect EIA whereas Furosemide does it. These differences results may be related to the differents mechanisms of action of the two diuretics.
-
Allergol Immunopathol (Madr) · Mar 1996
Randomized Controlled Trial Comparative Study Clinical TrialTime course of methacholine induced bronchoconstriction during drugs and spontaneous resolution.
We examined the resolution of the bronchial spasm induced by methacholine after administration of a dose sufficient to provoke PD20 to study, in patients with bronchial asthma, how spontaneous resolution (as opposed to bronchodilator-induced resolution) takes place. According to a randomization criterion, the patients were divided into four groups: 1) resolution induced by salbutamol (S), 2) by ipratropium bromide (I), 3) after placebo (P) and 4) spontaneous resolution (R). ⋯ On the whole, this phenomenon shows that pharmacological treatment accelerates the process of spontaneous resolution of the bronchial spasm induced by methacholine which, in our experience, beings to show after 15 minutes, and that after 60 minutes, there are no statistically significant differences in the four groups. It is our opinion that closer examination of this phenomenon may provide greater knowledge of the mechanisms that come into play during the phase after stimulation of the muscarinic receptors and that reasonably involve the system to eliminate the muscarinic drug.