The British journal of dermatology
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Randomized Controlled Trial Multicenter Study Clinical Trial
A randomized, placebo-controlled, double-blind trial of ondansetron in renal itch.
Renal itch is a relatively common and distressing problem for patients with chronic renal failure. Ondansetron, a serotonin type 3 receptor antagonist was developed for relief of chemotherapy induced nausea. Recently, anecdotal reports describe relief of renal itch with ondansetron. ⋯ Our results show that ondansetron is no better than placebo in controlling renal itch.