Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · May 1997
Randomized Controlled Trial Clinical TrialThe effect of acute normovolemic hemodilution on homologous blood requirements and total estimated red blood cell volume lost.
Acute normovolemic hemodilution combined with retransfusion is one of the various techniques proposed to avoid homologous blood transfusion in cardiac surgery. The purpose of the present paper is to study the effect of the volume of autologous blood collected pre-cardiopulmonary bypass (CPB) on homologous blood requirements and total estimated red blood cell (RBC) volume lost in coronary artery bypass grafting (CABG) surgery. ⋯ Acute intraoperative hemodilution with high- and low-volume phlebotomy reduced the homologous blood requirements similarly regardless of the amount of phlebotomy.
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Acta Anaesthesiol Scand · May 1997
Randomized Controlled Trial Clinical TrialIntrathecal morphine for post-sternotomy pain in patients with myasthenia gravis: effects on respiratory function.
Thymectomy can induce a remission or at least an improvement in myasthenia gravis (MG) patients. After sternotomy MG patients with compromised muscle strength need an excellent postoperative pain relief. This study was designed to evaluate the efficacy of intrathecal morphine (ITM) on ventilatory function among MG patients undergoing trans-sternal thymectomy, when intravenous morphine served as control. ⋯ Intrathecal morphine provided effective postoperative analgesia and significantly improved ventilatory function when compared with intravenous morphine.