Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Sep 1997
4-Chloro-m-cresol test--a possible supplementary test for diagnosis of malignant hyperthermia susceptibility.
In vitro contracture test (IVCT) for diagnosis of MH in our laboratory has a sensitivity of 100% and a specificity of 93%. The results are equivocal in 10-15%, and supplementary tests may thus be required. We have tested the hypothesis that 4-chloro-m-cresol (4-cmc) may be useful for a supplementary test. ⋯ 4-chloro-m-cresol may be a suitable aid to clarify puzzling results of standard testing of MH susceptibility.