Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Aug 1998
Randomized Controlled Trial Comparative Study Clinical TrialPostural post-dural puncture headache after spinal and epidural anaesthesia. A randomised, double-blind study.
This study was conducted in order to investigate the effect of patient expectation in the development of postural post-dural puncture headache (PPDPH). ⋯ SA gave more headache but superior quality of surgical anaesthesia compared with EA. Dural puncture, and not expectation, is the major cause of PPDPH.
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Acta Anaesthesiol Scand · Aug 1998
Randomized Controlled Trial Clinical TrialThe analgesic effect of racemic ketamine in patients with chronic ischemic pain due to lower extremity arteriosclerosis obliterans.
Ketamine in sub-dissociative doses has been shown to have analgesic effects in various pain conditions, including neuropathic and phantom-limb pain, where conventional treatment has often failed. Chronic ischemic pain due to lower extremity arteriosclerosis obliterans often responds poorly to analgesics, and the pain-generating mechanisms are not well understood. ⋯ We have demonstrated a potent dose-dependent analgesic effect of racemic ketamine in clinical ischemic pain. Due to a narrow therapeutic window, this analgesic effect is probably best utilised in combination with other analgesics.
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Acta Anaesthesiol Scand · Aug 1998
Randomized Controlled Trial Comparative Study Clinical TrialAnalgesic efficacy and safety of preoperative versus postoperative ketorolac in paediatric tonsillectomy.
Tonsillectomy is a common procedure in childhood resulting in significant morbidity due to pain. The aim of this study was to evaluate the analgesic efficacy and safety of a single dose of ketorolac i.v. given before or after tonsillectomy, compared to placebo. ⋯ This study indicates that a single dose of ketorolac 1 mg.kg-1 i.v. administered either before or immediately after surgery improves postoperative analgesia in children after tonsillectomy without evidence of increased incidence of bleeding.
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Acta Anaesthesiol Scand · Aug 1998
Randomized Controlled Trial Comparative Study Clinical TrialPostoperative analgesia with epidural bupivacaine and low-dose fentanyl--a comparison of two concentrations.
The purpose of the study was to compare the analgesic and side effects of two epidurally administered mixtures of bupivacaine and fentanyl with the same drug ratios. ⋯ Both groups had low pain scores with few and comparable adverse effects. It thus seems that the volume is not important when mixtures of bupivacaine and fentanyl in the studies concentrations are infused epidurally at a low thoracic level. Practical reasons favour the higher concentration mixture.
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Acta Anaesthesiol Scand · Aug 1998
Randomized Controlled Trial Comparative Study Clinical TrialTotal intravenous anaesthesia with propofol and remifentanil in paediatric patients: a comparison with a desflurane-nitrous oxide inhalation anaesthesia.
Remifentanil is a new rapid-acting and ultra-short acting mu-opioid receptor agonist with few reports from use in children. Therefore, we compared a propofol-remifentanil-anaesthesia (TIVA) with a desflurane-N2O-anaesthesia (DN) with particular regard to the recovery of characteristics in children. ⋯ In children, TIVA with remifentanil and propofol is a well-tolerated anaesthesia method, with a lower peroperative heart rate and less postoperative agitation compared with a desflurane-N2O based anaesthesia.