Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Nov 2000
Randomized Controlled Trial Meta Analysis Clinical TrialDroperidol and 5-HT3-receptor antagonists, alone or in combination, for prophylaxis of postoperative nausea and vomiting. A meta-analysis of randomised controlled trials.
Droperidol and 5-HT3-receptor antagonists are among the most potent antiemetics to prevent postoperative nausea and vomiting (PONV). Combinations of these drugs have been used to increase the efficacy of antiemetic treatment. However, so far the quantitative effect of this combination has not been evaluated systematically. ⋯ The data on the combination of droperidol with 5-HT3-receptor antagonists suggest that there is a trend towards increased efficacy of the combination therapy compared to the single drugs. However, so far there are insufficient data to recommend this combination treatment for prophylaxis.
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Acta Anaesthesiol Scand · Nov 2000
Randomized Controlled Trial Comparative Study Clinical TrialDoes efficacy of seal and fibreoptic view change during anaesthesia with the laryngeal mask airway: a comparison of oxygen and oxygen-nitrous oxide gas mixtures.
We test the hypothesis that oropharyngeal leak pressure (OLP) and fibreoptic position (FP) are stable for the laryngeal mask airway (LMA) during anaesthesia with and without nitrous oxide. ⋯ We conclude that OLP and FP are stable for the LMA during anaesthesia lasting 30 min with or without nitrous oxide.