Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jul 2000
ReviewLocal infiltration with NSAIDs for postoperative analgesia: evidence for a peripheral analgesic action.
In order to investigate the evidence for a peripheral analgesic effect of local infiltration with nonsteroidal antiinflammatory drugs (NSAIDs) in postoperative pain, we conducted a systematic review. ⋯ There is evidence for a clinically relevant peripheral analgesic action of intra-articular NSAIDs while results of IVRA and wound infiltration with NSAIDs in postoperative pain are inconclusive. Trials without a systemic control group were not considered to provide evidence for a local effect.