Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Sep 2000
Randomized Controlled Trial Comparative Study Clinical TrialOnset and offset of intrathecal morphine versus nalbuphine for postoperative pain relief after total hip replacement.
We designed this study to compare the postoperative analgesic effects of intrathecal morphine and nalbuphine, the endpoints being onset and offset of action. ⋯ We conclude that after total hip replacement, administration of intrathecal nalbuphine resulted in a significantly faster onset of pain relief and shorter duration of analgesia than intrathecal morphine.
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Acta Anaesthesiol Scand · Sep 2000
Randomized Controlled Trial Clinical TrialRandomised, placebo-controlled study of the postoperative analgesic effects of ketoprofen after spinal fusion surgery.
The additive effect of non-steroidal anti-inflammatory drugs administered with propacetamol after major orthopaedic surgery has not been studied. Thus, we performed a prospective, placebo-controlled study to assess the analgesic effects of ketoprofen in patients undergoing spinal fusion surgery and receiving propacetamol. ⋯ Ketoprofen reduced morphine requirements and improved postoperative analgesia in patients undergoing major spinal surgery and receiving propacetamol.
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Acta Anaesthesiol Scand · Sep 2000
Randomized Controlled Trial Clinical TrialEffects of intraperitoneal lidocaine combined with intravenous or intraperitoneal tenoxicam on pain relief and bowel recovery after laparoscopic cholecystectomy.
Previous work has demonstrated that intraperitoneal (i.p.) lidocaine may provide analgesia after laparoscopic cholecystectomy. The aim of this prospective, randomized, double-blind study was to compare pain relief, recovery variables, and side effects after i.p. instillation of lidocaine plus tenoxicam given either i.v. or i.p. after laparoscopic cholecystectomy. ⋯ Combination of intraperitoneal lidocaine and tenoxicam provided better analgesia on movement, and faster return of bowel function compared with i.p. lidocaine and i.v. tenoxicam during the 24 h period after surgery.
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Acta Anaesthesiol Scand · Sep 2000
Comparative Study Clinical Trial Controlled Clinical TrialA comparison of three doses of sufentanil in combination with bupivacaine-adrenaline in continuous epidural analgesia during labour.
Sufentanil is now frequently added to local anaesthetic in labour epidural analgesia. However, this opioid has some side effects such as pruritus, and in higher doses could harm the neonate. The purpose of this study was to compare three doses of sufentanil combined with low-dose bupivacaine, to determine the lowest appropriate dose. ⋯ We found no difference in the analgesic effect between three different concentrations of sufentanil. We conclude that the lowest dose may be used. This should decrease the risk of adverse effects on mother and child.