Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jan 2004
Randomized Controlled Trial Clinical TrialPropofol and remifentanil for intubation without muscle relaxant: the effect of the order of injection.
Common practice in intubation without muscle relaxant is to inject the opioid drug prior to the hypnotic drug. Because remifentanil reaches adequate cerebral concentration more rapidly than does propofol, we tested the hypothesis that injection of remifentanil after propofol might lead to better intubating conditions. ⋯ We therefore conclude that in premedicated healthy patients with no anticipated risk of difficult intubation, intubating and haemodynamic conditions are better when remifentanil is injected after propofol.