Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Feb 2007
Comparative StudyOutcome from intensive care after cardiac arrest: comparison between two patient samples treated in 1986-87 and 1999-2001 in Finnish ICUs.
The aim of the study was to find out whether the characteristics of patients and the outcome from intensive care after cardiac arrest have changed over time. ⋯ Since the late 1980s, the outcome from intensive care after cardiac arrest may have improved especially among younger patients and males.
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Acta Anaesthesiol Scand · Feb 2007
Moderate superficial hypothermia prolongs bleeding time in humans.
In vitro and in vivo studies have shown that mild systemic hypothermia influences platelet adhesion and aggregation and coagulation reactions. We wanted to test the hypothesis that mild local hypothermia in healthy volunteers with preserved core temperature increased bleeding time. A secondary aim was to evaluate if local cooling influenced whole blood coagulation measured by thrombelastograph (TEG) in the same setting. ⋯ Lowering the skin temperature from 32 degrees C to 30 degrees C and 28 degrees C with a preserved core temperature more than doubled the bleeding time. Whole blood coagulation measured by TEG was not influenced by the local cooling. In addition to core temperature, local temperature may offer information in understanding the surgical site of bleeding.
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Acta Anaesthesiol Scand · Feb 2007
Randomized Controlled Trial Multicenter StudyDoes esomeprazole prevent post-operative nausea and vomiting?
Esomeprazole is a potent proton pump inhibitor (PPI), reducing acid production as well as gastric juice volume. This study evaluated the possible beneficial effect of esomeprazole on reducing post-operative nausea and vomiting (PONV). ⋯ Esomeprazole had no clinically relevant effect on the overall 24-h incidence of PONV. However, esomeprazole significantly reduced the total amount of vomit during 24-h post-operatively. This may be of value in patients with an increased risk of pulmonary aspiration.