Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Nov 2010
Randomized Controlled TrialEffect of an intravenous infusion of lidocaine on cisatracurium-induced neuromuscular block duration: a randomized-controlled trial.
Intravenous lidocaine can be used intraoperatively for its analgesic and antihyperalgesic properties but local anaesthetics may also prolong the duration of action of neuromuscular blocking agents. We hypothesized that intravenous lidocaine would prolong the time to recovery of neuromuscular function after cisatracurium. ⋯ No significant prolongation of spontaneous recovery of a TOF ratio ≥ 0.9 after cisatracurium was found in patients receiving intravenous lidocaine.
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Acta Anaesthesiol Scand · Nov 2010
Randomized Controlled TrialThe effect of remifentanil on cough suppression after endoscopic sinus surgery: a randomized study.
Excessive coughing may increase the risk of complications after sinus surgery. We hypothesized that remifentanil would decrease the incidence and severity of coughing after endoscopic sinus surgery with propofol and remifentanil anaesthesia. ⋯ Maintaining anaesthesia with remifentanil to the end of the surgery, until after extubation, can suppress coughing without prolonging the recovery from anaesthesia. This effect is dose dependent and is more pronounced at higher concentrations of remifentanil (2.0 or 2.5 ng/ml).
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Acta Anaesthesiol Scand · Nov 2010
Randomized Controlled Trial Comparative StudyPerisciatic infusion of ropivacaine and analgesia after hallux valgus repair.
Moderate to severe pain after hallux valgus repair can be successfully treated with a continuous popliteal sciatic nerve block in ambulatory patients. Different anesthesiologists use various infusion rates for this purpose. The aim of this study was to compare the analgesic efficacy of two infusion rates of ropivacaine 2 mg/ml: 5 and 8 ml/h. ⋯ We found no significant difference in the analgesic effect between two perisciatic infusion rates of ropivacaine 2 mg/ml (5 vs. 8 ml/h) in ambulatory patients who underwent chevron osteotomy.
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Acta Anaesthesiol Scand · Nov 2010
Randomized Controlled TrialHuman opioid μ-receptor A118G polymorphism may protect against central pruritus by epidural morphine for post-cesarean analgesia.
Intrathecal or epidural morphine used for post-operative analgesia frequently induces central type pruritus. The purpose of this study was to investigate the association between the severity of central type pruritus induced by epidural morphine for post-cesarean analgesia and the A118G polymorphism of the human μ-opioid receptor gene (OPRM1). ⋯ The incidence of significant pruritus in the recessive type (GG) was significantly lower compared with the dominant types (AA+AG). The recessive G allele in the A118G polymorphism may have protective effects against significant pruritus after epidural morphine for post-cesarean analgesia.