Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Feb 2010
Comparative StudyComparison of desaturation and resaturation response times between transmission and reflectance pulse oximeters.
In general, there is a response time between actual arterial hypoxemia and its detection by pulse oximeters. We compared the desaturation and resaturation response times between two types of pulse oximeters, transmission and reflectance pulse oximeters, to find out which oximeter has a more rapid response time. ⋯ In clinical situations in which rapid changes in oxygen saturation are expected, we recommend the forehead reflectance pulse oximeter because it responds more quickly in detecting oxygen desaturation and resaturation compared with the transmission pulse oximeter.
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Acta Anaesthesiol Scand · Feb 2010
Randomized Controlled Trial Comparative StudyEndotracheal tube size and sore throat following surgery: a randomized-controlled study.
Women experience less frequent and less severe sore throat postoperatively after intubation with a size 6.0 ETT versus size 7.0.
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Acta Anaesthesiol Scand · Feb 2010
Randomized Controlled Trial Comparative StudyUnilateral paravertebral block: an alternative to conventional spinal anaesthesia for inguinal hernia repair.
Inguinal herniorrhaphy can be successfully performed using general, regional or local anaesthesia. Paravertebral block (PVB) has been used for unilateral procedures such as thoracotomy, breast surgery, chest wall trauma, hernia repair or renal surgery. ⋯ It can be concluded that unilateral PVB is more efficacious than conventional SA in terms of prolonging post-operative analgesia and reducing morbidities in patients undergoing elective unilateral inguinal hernia repair.
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Most studies on trauma and trauma systems have been conducted in the United States. We aimed to describe the factors predicting mortality in European trauma patients, with focus on triage. ⋯ Around 50% of all trauma deaths occurred at the scene. Increased survival of severely injured patients may be achieved by early transfer to highly specialised care.
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Acta Anaesthesiol Scand · Feb 2010
Impact of the CYP2D6 genotype on post-operative intravenous oxycodone analgesia.
Oxycodone is a semi-synthetic opioid with a mu-receptor agonist-mediated effect in several pain conditions, including post-operative pain. Oxycodone is metabolized to its active metabolite oxymorphone by O-demethylation via the polymorphic CYP2D6. The aim of this study was to investigate whether CYP2D6 poor metabolizers (PMs) yield the same analgesia post-operatively from intravenous oxycodone as extensive metabolizers (EMs). ⋯ This study showed for the first time in patients that the oxymorphone formation depends on CYP2D6, but we found no difference in the post-operative analgesic effect of intravenous oxycodone between the two CYP2D6 genotypes.