Acta anaesthesiologica Scandinavica
-
Acta Anaesthesiol Scand · Feb 2010
Comparative StudyDepth of anaesthesia and post-operative cognitive dysfunction.
A deep level of anaesthesia measured by the bispectral index has been found to improve processing speed as one aspect of cognitive function after surgery. The purpose of the present study was to assess the possible effect of the level of anaesthesia on post-operative cognitive dysfunction (POCD) 1 week after surgery, as assessed by a neuropsychological test battery. ⋯ We were unable to detect a significant association between the depth of anaesthesia and the presence of POCD 1 week after the surgery.
-
Acta Anaesthesiol Scand · Feb 2010
Randomized Controlled Trial Comparative StudyCorrelation and agreement between the bispectral index vs. state entropy during hypothermic cardio-pulmonary bypass.
The bispectral index (BIS) and spectral entropy enable monitoring the depth of anaesthesia. Mild hypothermia has been shown to affect the ability of electroencephalography monitors to reflect the anaesthetic drug effect. The purpose of this study was to investigate the effect of hypothermia during a cardio-pulmonary bypass on the correlation and agreement between the BIS and entropy variables compared with normothermic conditions. ⋯ Acceptable agreement was observed between the BIS and entropy variables under normothermic but not under hypothermic conditions. The BIS and entropy variables may therefore not be interchangeable during a hypothermic cardio-pulmonary bypass.
-
Acta Anaesthesiol Scand · Feb 2010
Randomized Controlled Trial Comparative StudyModafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills.
Early recovery of patients following sedation/analgesia and anesthesia is important in ambulatory practice. The aim of this study was to assess whether modafinil, used for the treatment of narcolepsy, improves recovery following sedation/analgesia. ⋯ Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve recovery in terms of objective measures of patient psychomotor skills.
-
Acta Anaesthesiol Scand · Feb 2010
Comparative StudySurface vs. aortic flush cooling during cardiac arrest in pigs.
To investigate the feasibility and efficacy of earlier induction of hypothermia already during the 'no-flow' period of cardiac arrest with non-invasive surface cooling or invasive aortic flush cooling. ⋯ Invasive cooling by aortic flush with cold saline rapidly induces deep cerebral hypothermia, whereas non-invasive surface cooling only marginally decreases brain temperature.