Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Nov 2011
Randomized Controlled TrialDexamethasone has additive effect when combined with ondansetron and droperidol for treatment of established PONV.
Prophylactic dexamethasone, ondansetron and droperidol have a documented effect on post-operative nausea and vomiting (PONV). Still, there is a lack of studies investigating the effect of adding dexamethasone to ondansetron and droperidol in order to treat established PONV. ⋯ Treatment of established PONV comprising ondansetron and droperidol, with or without dexamethasone, reduced PONV in both treatment groups. In those reporting PONV without active prophylaxis, the addition of dexamethasone resulted in a significant amplification of the PONV-reducing [corrected] effects of ondansetron and droperidol.
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Acta Anaesthesiol Scand · Nov 2011
Randomized Controlled TrialDose-dependent attenuation by fentanyl on cough during emergence from general anesthesia.
Although fentanyl suppresses tracheal tube-induced cough during anesthetic recovery, it has not been proven if its antitussive effect is dose dependent and complication free. The purpose of this study is to evaluate the relationship between fentanyl doses and cough suppression during emergence from sevoflurane anesthesia. ⋯ Fentanyl suppressed cough in a dose-related manner during recovery from general sevoflurane anesthesia, and 2 mcg/kg may be considered as a proper dose.