Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Nov 2012
Randomized Controlled TrialThe perioperative combination of methadone and ketamine reduces post-operative opioid usage compared with methadone alone.
A synergy between ketamine and methadone (ME) to produce antinociception has been demonstrated in experimental neuropathy. We wanted to compare post-operative opioid requirements in patients undergoing multilevel lumbar arthrodesis after the administration combined ME-ketamine (MK) or ME alone. ⋯ Perioperative ketamine-ME combination significantly decreased opioid consumption by PCA.
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Acta Anaesthesiol Scand · Nov 2012
Randomized Controlled TrialNaloxone infusion and post-hysterectomy morphine consumption: a double-blind, placebo-controlled study.
The evidence that an infusion of a low dose of naloxone reduces post-operative pain and opioid analgesic consumption is somewhat conflicting. Thus, the aim of the present study was to investigate the effect of an ultra-low dose of naloxone on patient-controlled morphine analgesia. ⋯ Following hysterectomy, an ultra-low dose of naloxone infusion proved to reduce morphine consumption as well as the incidence and severity of opioid-induced nausea and vomiting.
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Acta Anaesthesiol Scand · Nov 2012
Randomized Controlled TrialA smaller endotracheal tube combined with intravenous lidocaine decreases post-operative sore throat - a randomized controlled trial.
Post-operative sore throat (POST) has increasingly been a common clinical complication particularly in thyroid surgery. We conducted a trial to evaluate the effect of non-pharmacological [smaller-sized endotracheal tube (ETT)] combined with pharmacological intervention [lidocaine intravenous (i.v.)] on POST in women undergoing thyroid surgery. ⋯ Use of smaller-sized ETT combined with i.v. lidocaine decreases the incidence and severity of POST in women undergoing thyroid surgery.
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Acta Anaesthesiol Scand · Nov 2012
Randomized Controlled Trial Comparative StudyLMA ProSeal(TM) vs. i-Gel(TM) in ventilated children: a randomised, crossover study using the size 2 mask.
The Laryngeal Mask Airway (LMA) ProSeal(TM) and the i-Gel(TM) are two extraglottic devices with either an inflatable cuff or a non-inflatable cuff. ⋯ We conclude that oropharyngeal leak pressure and fiberoptic position of the airway tube are similar for the size 2 LMA ProSeal(TM) and i-Gel(TM) in non-paralysed ventilated children.